Recombinant Human TNFRSF11A/Rank Protein, hFc TagSynonyms NF KB; Receptor activator of NF KB; ODFR; CD265 Source Human TNFRSF11A Rank Protein is expressed from HEK293 with hFc tag at the C Terminus. It contains Ile30 Pro212.[Accession Q9Y6Q6 1] Molecular Weight The protein has a predicted MW of 46. 85 kDa. Due to glycosylation, the protein migrates to 55 65 kDa based on SDS PAGE result. Endotoxin Less than 1EU per g by the LAL method. Purity > 95% as determined by SDS PAGE and HPLC. Activity ELISA

hFc Tag captured on CM5 Chip via Protein A can bind Human APOE

survival and activation of NK cells

and a 74 aa cytoplasmic region

QIAPPCTSEK HYEHLGRCCN KCEPGKYMSS KCTTTSDSVC LPCGPDEYLD SWNEEDKCLL HKVCDTGKAL VAVVAGNSTT PRRCACTAGY HWSQDCECCR RNTECAPGLG AQHPLQLNKD TVCKPCLAGY FSDAFSSTDK CRPWTNCTFL GKRVEHHGTE KSDAVCSSSL PARK

The protein has a predicted MW of 50 kDa

but contains both the beta and gamma subunits

High toxicity

13(4):2131-2141

2 μm filtered concentrated solution in 20 mM Tris-HCl

Ser510-Ser630

[1] Chen J

end repair